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What's the potential to weaponize such advances, say by creating novel prions and so on? I assume powers that be are already playing with the tech hidden away in their bunkers?

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Probably limited as far as prions go. This particular advancement is in proteins that have sought-after mechanical properties like spider silk.

If you wanted to cultivate prions as a bioweapon, you could already grab them from reservoir sources such as deer and cattle.

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