No, you can't really. You can just say "simplify" but it does not convey the same message.
That is, it conveys a suggestion to simplify (the first part) but it doesn't convey that simplification has so extreme importance that it's worth to repeat the message (the second part).
It's not like I thought of it as a serious question, I just added it for the benefit of anyone confused by the contradiction.
Fuck, if I have to be a pedant, I'd better go all the way: well, they might be, but
1) they don't use * as the multiplication symbol, but ~ "x".
2) they don't multiply words and numbers... Repeating a string this way is something programmers do.
I don't think anyone will have difficulty grasping that 'Simplify Simplify Simplify' and 'Simplify x 3' can be considered equal.