I upgraded my 10 year old PC to Ryzen 5000 a couple of years back, and have never really looked back. Sure, it wasn't that long until 7000 supplanted it, but my PC is still just fine, and will likely be for the next 7 years or so (the biggest wild card is Windows support).

The only thing I really regret is getting a B450 Motherboard that only supports 1 NVMe SSD (and only PCIE Gen 3 SSDs). I would focus on making sure your motherboard has enough RAM and SSD expansion room, and then buy a big enough power supply for whatever GPU you want to run. You might want to figure out whether Zen 5 will have a new chipset, and if so, will the IO be significantly better. Nothing else is going to make a huge difference.