I'm not super familiar with the East Palestine derailment, but based on what I do know about it I think your 59/60 train cars example is sort of disingenuous. American freight rail operators are well known for skimping on safety in multiple dimensions; issues like obsolete brake technology, stretched-thin crews, insufficient maintenance, and excessively long/heavy trains have all been discussed to death before and after that accident. The problem isn't some off-by-one miscalibration, but rather that our regulators (and I'm including lawmakers under that umbrella, especially since they're usually the ones taking the bribes AFAIK) are simply not willing to demand that these industries put public safety over profits in areas where there are well-understood systemic safety problems. AIUI, efforts to improve rail safety during the 2010s and earlier have been largely stillborn, sabotaged by rail company lobbying.
Just to illustrate what I'm talking about via another example: if the MCAS system that killed 346 passengers on two 737 Max aircraft within the span of a few months had been an honest design flaw rather than a hack devised to juice sales by dodging retraining requirements, cheaply and shoddily implemented ignoring the misgivings of Boeing personnel and rubber-stamped by the FAA, then it would have been a simple tragedy. As it actually happened, it's an atrocity—a failure on multiple levels by many people who ought to have known better, holes in the Swiss cheese all lining up, 346 lives sacrificed on the altar of avarice. That's where the invisible hand gets you when you let it take the wheel, but I suppose next you'll tell me that those people ought to have done their own safety audits of the aircraft that got them killed.