I have a Tuxedo Aura Gen 3 (I think), on arch. Works well, no issue to mention. Their custom kernel module and control center that goes with is is available in the aur.

A friend of mine has a Tuxedo Pulse 14 (if I remember correctly) and he is using openSUSE Tumbleweed with KDE Plasma on it and he sounds very happy about it.

I have a TUXEDO Pulse 15 - Gen1 for almost 4 years now. And I am running Debian. Works great for me.