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It's not self-destruct, but you can quickly lock your phone if you are worried about handing your phone to an adversary.

Quickly press the power button 5 times. This makes it so you have to enter your passcode to use the phone (ie no biometrics).

The phone can probably still be accessed via rubber-hose cryptanalysis.

You could probably do a self-destruct with this technique by also having something generate and automatically set a random password.

I think the default is 10 incorrect passcodes wipes the device.

In that case it sounds like there is already a self-destruct button!

You can also hold down power and a volume key to lock an iPhone and require the passcode.