Normal BT drops to very low sound quality when the mic is in use, because it goes into "headset" mode. Apple got around that with an extension. Combined with the jank pairing and device switching, the difference is pretty big.
[0] https://www.logitech.com/en-us/products/keyboards/mx-keys-mi...
There are also some BT limitations at play. Key rollover is capped, and mouse polling rate is lower. But that'd only matter to me if I were playing PC games. Ability to switch devices is a plus for BT.