The J-curve charts I've seen indicated lowest all-cause mortality at 3 drinks / week for men and 2 drinks / week for women. So even if you believe there's something healthy to alcohol (and it's not just the unhealthy people -> have to drink 0), it probably won't be any healthier going past 3 or 2 / week. Portion size is 12oz 5% beer, 5 oz 12% wine, 1.5oz 40% liquor.