Jeez those toolbars are ridiculous. When the content part of your UI is 60% of the window, something has gone very, very wrong.
Add these on to Web interfaces, which are increasingly (hullo, Google?) trending toward persistent, non-scrollable header/footer elements, and I'll find myself on websites in which perhaps 25% of my screen is available for my present task.
And that's using an interface which already minimizes browser and desktop GUI intrusions (Firefox/Vimperator and WindowMaker).
I wish I could move Xcode4's "iTunes-style" header to the bottom of the window when coding on 13".
Casual users do not want to think about raw files, let alone how to move them around the filesystem. That is why all modern operating system don't expose these concepts.
You don't fix this kind of problem by making the buttons bigger.