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The clause preceding that quote gives you the answer:

> if you have never had dengue and you take Dengvaxia, it paradoxically increases the odds of getting a bad case

e.g. if you have had dengue previously, it reduces your chances of having a bad case to 20% (according to that comment).

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And, critically, once you have one serotype of dengue, your chances of severe dengue from infection by another serotype are substantially higher.

First dengue is often not that bad. Second dengue is often quite bad. This vaccine makes second dengue not that bad, but if you take it without having had first dengue, it just leaves you in the same boat as if you’d had first dengue — worse off than if you’d had no dengue.

Can confirm this. The second attack is potentially fatal.

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