They offer some extra's like MagicDNS, go/, ssh auth, etc
But no, if you don't need that and if you've done the setup part, and you're just looking at the VPN part, you wouldn't gain anything.
Tailscale magically works, recovers well from crashes/network changes (I've had a few issues here with WG native client), manages your keys (and rotation of), creates point to point tunnels (which is just confusing via a plain text config with several devices).