We'll have nice and easy support for self-hosting soon-ish.
In the meantime, everything is open-source and the infra is codified with Terraform. GCP should have the best support now. If you want to dig into it, we'd love to give you support along the road so we can improve the process.
Our infra repo [0] is a good place to start. Once you have E2B deployed, you can just change E2B_DOMAIN env var and use our SDK.
Feel free to email me, join our Discord, or open an issue if you have any questions