In terms of profiling - some folks are sick of theft - so the sentiment change if they start taking a harder line on theft may be smaller than you think. The profiling is easy. Pushing a shopping cart past the registers and out the front door without paying.
A local place cracked down majorly on this - I think it's been good for the business. The locked up merchandise is an absolute mess to deal with though - they don't have enough staff and so much is locked up so you spend a lot of time waiting to get stuff. I've started going to another location of this one store that is in an area much less impacted by retail theft - it is night and day just in atmosphere and accessibility.