If we can convince the companies to actually try for compatibility, then a revival of MXM is probably a significantly better option.
In framework's case, the cooling is integrated in the gpu module, and both it's size, cooling and power deliver can be adjusted depending on the gpu power.
A friend of mine was betrayed on this by MSI, where laptops with GTX 900 series GPUs were promised upgrades and then when the 1000 series came out they didn't offer any. I think they did make weak excuses about power use, but a 1060 would have fit within the power budget fine and been an enormous upgrade. A few people have even gotten 1060 modules to work with BIOS edits, so it wasn't some other incompatibility. It seems like they saw they couldn't offer a 1080 and threw out the entire project and promise, and then offered a mild discount on a brand new laptop, no other recourse.