No, the reason for less than stellar performance of Lisp on the 32bit x86 CPUs were things like too few registers.

On 64bit Intel CPUs this is much less of a problem and Lisp runs roughly twice as fast in 64bit mode. I would think that this even holds without taking advantage of wider data words.

On other architectures this was less of a problem. 32bit CPUs had more registers on a RISC or some other CISC CPUs.