> Worth noting that they did release the AlphaFold 2 weights after a while.

Yes - though I don't think Isomorphic labs existed at that point.

Obviously the real reason AlphaFold was possible was the huge tax payer funded effort running over decades to generate a diverse, high quality 3D structure dataset.

However that's why we put taxes into research - to spur innovation in a pre-competitive way - so that's fine.

What's not fine is any benefiting company avoiding paying any tax back on resulting profits - that's just free riding - and many of the big tech companies are, in my view, guilty.