Typically when one starts a Lisp development system, it will always start some kind of visible REPL. Either it runs it in a Terminal (most UNIX Lisps have a terminal REPL), runs it as a tool in its own GUI-based IDE (MCL, CCL, Allegro CL, LispWorks, Corman Lisp, ..., Symbolics Genera, CL + McCLIM) or runs the REPL frontend in a connected IDE (-> SLIME + GNU Emacs is a prominent IDE for CL, earlier this was done using subprocesses called "inferior Lisps" like in ILISP+GNU Emacs).
The conversational REPL interface (typing expressions, evaluating the expression and getting a response) is widely used.
Smalltalk has the "Workspace" or a Playground (-> Pharo) as similar tools.