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I'm not sure about that, there haven't been too many large European tech companies growing up in the aftermath of GDPR. While it's probably a small factor, I do think this general climate of regulation hurts smaller companies more than is generally acknowledged.

It is not a non-issue.. i promise you GDPR shifted and continues to shift massive amounts of tech capital from the EU.

many major tech firms skip launching entire products in the EU nowadays due to gdpr and DMA

They're by far not done regulating. Upcoming ones like Cybersecurity Act will be pretty burdensome to deal with if they don't turn out right.