No, it's not. I've been happily running Linux on my personal machines for more than two decades.

> what about those who rely on software that is only available on Windows and macOS?

Matlab is the software in question in this particular case, and as others have already posted, it runs on Linux.

Even for particular software that might be Windows/Mac only, there are almost always functional equivalents that run on Linux. For example, OpenOffice (and later LibreOffice, which is what I run now) as an alternative to MS Office.

I have had plenty of opportunity for comparison because, for all the time I have been running Linux on my personal machines, I have had to use Windows at work. I have always had much more hassle with my work machines, and if I had a dollar for every time I have had the thought that, if only my employer would switch to Linux on desktops, my work life would be so much easier and my productivity would be better, I'd be retired now. And that's not even counting all the times I have had the thought that if my employer would run Linux on servers instead of Microsoft crapware, our IT infrastructure would be so much more robust.

The one example I have seen in this discussion of software that is truly limited to Windows/Mac is Solidworks. But that's a particular product for a particular niche, not a general office application.