I've used calculus for physics simulations in games.
I had to do a bunch of performance analysis, and a little bit of knowing what distributions actually meant helped a lot. I regret not having taken more statistics in college.
I was talking with a philosophy prof once, and somehow we got to DeMorgan's theorem. "I use that nearly every day," I told him, and it kind of floored him -- apparently he considered it "advanced" logic.