They should be sent to prison for this, as should all fraudulent researchers big and small.
On one hand, these people have a big responsibility to do good work and stay out of trouble for the sake of the ones they're helping (i.e. Alzheimer's patients), but on the other hand their impact depends a lot on their mental/emotional state -- if you put more bs in their mental buffer, it's naturally going to mess with them and lead to a decline in quality. They have to focus.
Distrust in science is at an all time high and these frauds cause incalculable damage to scientific integrity. They are literally poisoning the well of human knowledge. That should be considered a high crime.