What is "low-fragmentation heap"? Why would anyone want "high-fragmentation heap"? (since you imply that it's an option)
Also it puts consequently allocated objects (of different size) far away (and thus reduces cache locality), which, in turn may reduce performance for some "allocate a lot of stuff at the beginning and then serve it", etc scenarios, but this is pretty esoteric problem.
Benefits outweigh the concerns, so most apps benefit from the low-fragmentation heaps.
For short-lived processes, it's faster and uses less memory. The code is also simpler (important if you're writing a malloc in the mid-1980s).