Iterm2’s remote tmux integration is a killer feature for me. Gives you a native, normal “windows and tabs” kind of feel, but for a remote connection. You can also disconnect/reconnect without losing your windows and tabs.
You don’t need to know any tmux to use it either (except for how to launch the right mode, which is easy to script).
If you spend a lot of time SSHed to other computers, I would highly recommend trying it out.