I guess it's the timber-over-concrete that is new and without historical example? Or regardless, the issue is that the historical examples are too expensive to build now. (Why isn't this an issue with residential too? I think it is actually?)
Here's a very typical generic Chicago example, which possibly has had it's ground floor facade replaced at some point in an uninspired way, but you can see the masonry on the upper floors (only 3-over-1) which would be an absolute premium luxury build today, and the building has plenty of character even though it's not being used for especially high-rent purposes at the moment: https://www.google.com/maps/@41.9654135,-87.6587315,3a,75y,2...
Here's a new construction (past 20 years anyway) 4-over-1 that is all brick... pretty boring and generic. Would people hate it as much as the timber-over-concrete? I have no idea. https://www.google.com/maps/@41.962424,-87.6661565,3a,75y,26...
Here's a pretty delightful and typical older all masonry 5-over-1, nothing special, tons of buildings like this. https://www.google.com/maps/@41.9582377,-87.6528717,3a,75y,8...
There is no lack of great historical examples of mid-rise 5-over-1 residential over retail -- but they probably aren't timber frame over concrete podium.