> Do you really think that the current situation poses a >25% cost on scientific productivity? Do you think your system would be able to recapture that?

Yes and yes. I'm 6 years past defending my PhD and I have low confidence in being able to reproduce results from papers in my field (computational biophysics).

I was recently at an industry-heavy biophysics conference that ran a speed dating event, and my conversation starter was "what fraction of papers in our field do you trust?". I probably talked to ~20 people, with a median response of ~25%.

Even a tiny amount invested in reproduction studies and accountability would go a long way. Most papers in _computational_ biophysics still don't publish usable code and data.