I've long dreamt of a system that compiles to native code, but stores a compressed SSA form (similar to SafeTSA or LLVM bitcode) in the binary for efficient runtime re-optimization based on profiling, somewhat similar to current Android Runtimes. One could then have several levels of debugging symbols, one that gives names to local variables represented by CFG nodes, and another that adds a compressed diff between some standardized decompiler output and the original source.

You could then decompile to some alternative syntax, but you'd lose any idiosyncratic formatting represented by the compressed diff.