Practically speaking, that is all the end-user can do with Windows machines. My point is Windows is fundamentally unsecure. It is a dike with thousands of holes some of which are not even visible to Microsoft themselves. The reason of that is security has been after-thought. It is band aids/plasters put on top of other plasters.
There are people in that category who are not hands-on themselves but still have sufficiently deep understanding of technical details. But as one might guess, they are about as common as four-leaf clovers.
I know everybody hates the C-word but if I look at 27001 requirements or the CIS benchmarks, there is nothing in there that I do not want for myself. If you can keep a list of the products and services you are running, have actually put the time into implementing it correctly, and have an ongoing maintenance plan then you are probably in the top 1% of networks.