If your system is a flight information display, then you may well have two userspace processes that do anything of significance: the display manager and the actual app. There is no persistent state. At this point, SELinux is purely overhead and extra attack surface — what would it even protect.
If your payload is a container (database server, microservice, whatever), and you’re doing some form of best-practice volume management, then only the database’s own data is mounted for it. SELinux is a real PITA to get working in a context like this, and it’s not really clear what it would add. (Okay, maybe you get fancy and use it to restrict what can talk to the microservice. Or maybe you use network namespaces.)
If you’re running a desktop or a more conventional server setup, then, sure, MAC policy has its place.