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The relevant quote I saw was this:

"These are changes he hasn’t noticed in patients who have lost significant weight in other ways—like through diet or gastric bypass surgery—which makes him think it’s unique to GLP-1 usage."

Are you suggesting sections elsewhere in the article suggest otherwise?

Not unlike the "massive muscle tone reduction" scare about GLP1 meds - you lose that muscle because you're also losing the fat you needed the extra muscle for...

> you lose that muscle because you're also losing the fat you needed the extra muscle for

That may be part of the cause, but it's also true that whenever you lose weight, you always lose some muscle. Even bodybuilders who are following the most aggressive protocol to minimize muscle loss (extremely high protein intake compared to other macros, along with intense strength training) will experience some amount of muscle loss along with fat loss when slimming down for competition.

It's not that clear. The article is specifically about this, is it just the speed or something else.

> "We’re still waiting to find out," says Dr. Few. "I don't think anybody can tell you definitively that there's not an inherent change to the skin."