Jupyter can run JS kernels these days.
Do you use it? Does it work well for you? I'm interested in learning more about your use case if you don't mind sharing.
You don't need to use the web client, all IDEs have jupyter integration these days, Zed even has it built-in. Just one "pip install" away.
People who want to move away from that welcome any alternatives, be it Mathematica or true open source replacements in TypeScript. Please port numpy to TypeScript, too!