Eh I mean it would depend on how your doing it really, Im thinking its the difference between "hey sorry to interrupt, I have a question do you have a minute?" vs "hey {question}"
For longer issues, could it make more sense to schedule an (online) meeting?
And on the receiving side of interruptions: Ocasionally it has helped me to just keep the "chat app" closed when I want to concentrate on something. If anyone has something urgent, they could always elevate to performing an old-style synchronous phone call, but interestingly this rarely happens with "text-chat" people :)