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Faster with Python ergonomics is Go. Safer with C++ perf is Rust.

(my rule of thumb)

If you haven't checked it out, nim sits at a really good middle ground for ergonomics, safety, and speed.

I haven't looked at it in years, but that's what I've been hearing indeed.

For faster with Python ergonomics,

Common Lisp, Scheme, Julia, OCaml, F#, C#, Scala, Kotlin, TypeScript, Clojure