LLM has been a boon for productivity of a lot of developer, but I have yet to see a radicaly novel product that could have only been made with LLM, do you have any example?
There are reports of using LLMs and ML in drug discovery and gene analysis. It might be a stretch to claim that it would be physically impossible for a human to do this, but it's making a dent in the "not enough hours in the day" part of the job. Not familiar with any novel software.
With fairness to non-AI computing, projects like Folding@Home also did this same task without any AI or ML. It wouldn't shock me if the power-per-discovery ratio was roughly similar too.