It can take several months of work to approve one single package to the official repos, for a single distribution. And each have different rules and setup.
Now explain to me how you think this is going to work.
Also, do you place to force everyone to use chroot or containers to replace their virtual env systems to have variations on deps? Or maybe everybody should use nix?
Do you want to do that also for JS, Ruby and PHP?
Not all PyPi projects require C code.
> It can take several months of work to approve one single package to the official repos
This is a massive exaggeration. For Fedora it takes a couple of days, all of it being necessary review of the code and licenses. And yes, you do have to do that work, it's done by the distros themselves too.
> Also, do you place to force everyone to use chroot or containers to replace their virtual env systems to have variations on deps? Or maybe everybody should use nix?
Nix is a good fit for this, but so is Guix and probably Spack. With a sane implementation of PEP-725 (which I mention and describe in another comment on this post), users could freely choose whatever package manager they like to supply non-Python deps.