Compiler speed and memory usage are the focus of the next quarter for Google.
PS - Great job on the presentation today. Sort of felt like it devolved into a marketing pitch (with Sencha et al.), but you're a hard act to follow!
1) dropping support for older browsers like IE6/IE8/Firefox 3.
2) using Soft Permutations (also known as capability checks in the JS work). GWT can automatically collapse permutations into capability checks. The downside is increase of JS code size.
Dart won't really solve this issue, but it more likely that it will just target modern browsers.
With GWT 2.5 and Elemental, you can drop back to HTML5 browsers only and use only 1 permutation.