Impotence and weight gain are not just "annoying" side effects. They seriously impact your life. Just putting that out there.
That's in contrast to psylocybin, which has substantially more serious potential acute side effects, ones that are more difficult to understand and treat should they occur.
I'm not saying psylocybin is unsafe or that SSRIs are always preferable. But if I'm asked to compare their safety? The choice is obvious, weight gain notwithstanding.
You were clearly implying they don’t when you downplayed all SSRI downsides as “a handful of annoying side effects”.
Weight gain kills. Suicidal ideation also kills many people when they start SSRIs. People have killed themselves because of permanent sexual dysfunction caused by SSRIs that never went away after stopping the drugs (and yes, this is a known possible adverse effect listed in the official prescribing information).
I don’t think the choice is as “obvious” as you’re making it out to be.
Leaving this link for others to pick up for more information: https://annals-general-psychiatry.biomedcentral.com/articles...