This is explained in the article:

“ That does happen, of course, but research shows that it is not the full story. A study of more than 17,600 overweight and obese patients from 41 countries who took semaglutide found that participants lost about 10% of their body weight and had a 20% reduction in serious adverse coronary events, strokes, heart attacks and all-cause mortality. Crucially, these cardiovascular improvements long preceded any meaningful weight loss. ”