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Yes, t-cell depletion which has resulted in a rise in the rates of other diseases showing up that were lower or under control before.

The UK government publishes data with counts of various things that you can make graphs from.

Could that T cell depletion have been caused by isolation and masking during the pandemic rather than covid directly?

In what way would this hypothesis make sense?

Decreased exposure to pathogens

While in a way true, I highly doubt it would be that significant unless there are studies showing that.