Doesn't do columns, but does do multiple tabs. I was reluctant to switch to tabs from columns too, but it's my preferred Mac client now.
Also supports a "mini" tweet view which makes it work more like an email client. http://yfrog.com/oerabxhp
Also supports a "mini" tweet view which makes it work more like an email client. http://yfrog.com/oerabxhp