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High CO2 levels impair cognition and stale air accumulates pathogens, not just smells. The V in your HVAC stands for Ventilation, so you're already getting fresh air, that's probably why you have no complaints. If you live in an air tight apartment with no forced circulation where CO2 levels spike super fast requiring ventilation several times a day, it's a different story.

In the winter it's cold outside and opening the window cools down the room -> no ventilation most of the time.

In the summer it's not a problem for me, I leave my windows partially open all the time but in the winter especially when working from home this would be quite neat. Also, I live in a small town in germany so the air quality here is comparatively good to many of the city folks here.

Possibly could help with radon poisoning