VSee (http://vsee.com/) doesn't look bad, but it's also closed sourced. Something built on open standards (SIP/XMPP) like Jitsi is likely to be more transparent because you won't have to guess what some mysterious supernode does and doesn't do with your data.

Good luck getting your non-techie friends to use that though. Skype became popular because it just worked, which at that point had not reliably been achieved even for plain voice calls, much less video.

Here's a start: http://alternativeto.net/SearchResult.aspx?search=tag%3avoip...