Aedan desoldered the RP2350 and physically cut the copper trace feeding voltage to a pin. Then he proceeded to use voltage glitching and was pretty open about how lucky he was, or in other words how unlucky Rasperry Pi Ltd. was for the attack to work.
Doesn't this sound like the RP2350 is "secure enough"? Like you mention, if the attacker can send a unit to an MCU Break service, it's game over already.