Doesn't matter too much if you're just using Dropbox as a storage backend for a more complex service. If your box is full of encrypted 2MB segments backing a pseudo-filesystem you can upload files as big as you like and not have to worry about broken connections.

The best part is that you can use other services with similar APIs for pseudo-RAID or just a union-mount. Sharing is more difficult than vanilla Dropbox, of course, but I'm working on it...