makemkv->mkv->handbrake->mp4 is pretty straightforward for saving media, especially if you don't mess with handbrake much (I just use one settings profile for everything). _Playing_ bluray directly from disk is a PITA because of needing to set up the encryption keys and extra system libraries.

The part that eats my time is converting the subtitles from an image format (vosub/psg) to a text format (srt), since the image formats have never worked well for me on plex. SubtitleEdit is good but it still takes manual managing.

Edit: I forgot about the annoyance of finding a drive that works with ripping software, iirc there's only a couple that will without flashing firmware