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Why would it be a deal breaker? uv would replace conda. And I hope it does. Conda has been such a headache for me when I've used it in the past. If the Python (particularly ML/academic community) could move on from conda it would be a great thing.

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uv can’t replace conda, any more than it can replace apt or nix.

Conda packages general binary packages, not just python packages. uv is just python packages.

Python packages (distributed via the Python package index, PyPI) can also be general binary packages. Try pip install cmake, for example.

Yes, but there are restrictions; for one thing, it's not trivial to share binary dependencies between Python packages; conda just handles that.

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