I'll say, I am as pessimistic as the next person about new ways to do X just to be hip. But as someone who works on many different Python projects day to day (from fully fledged services, to a set of lambdas with shared internal libraries, to CI scripts, to local tooling needing to run on developer laptops) - I've found uv to be particularly free of many sharp edges of other solutions (poetry, pipenv, pyenv, etc).
I think the fact that the uv tool itself is not written in Python actually solves a number of real problems around bootstrapping and dependency management for the tool that is meant to be a dependency manager.