I get pretty decent, if high-contrast results pushing 320TX and 400TX to 3200.
Pushing does increase grain; but using a larger format (6x7 or 4x5) reduces the apparent grain in resultant prints.
I can't say enough good things about HC-110 as a developer: pushes well just by increasing development time, shelf-stable for years as a concentrate, and not particularly toxic compared to other developers.