It says that the physical world is a collection of discrete events, doing away with continuous time. It also says that every event involves two systems, in that each event takes place in one system relative to another system.
The idea seems a little strange but the article gives a more intuitive example. It doesn't make sense to talk about the absolute velocity of a particle, only its relative velocity with respect to a reference frame.
But RQM takes it further. It brings to mind the old question about "If a tree falls in a forest and no one is around to hear it." I guess RQM would say that this question isn't even wrong.
The article quickly becomes too technical for me to understand, so I'm still confused about some aspects. For instance, if each event only involves two systems, how is it that we can have a whole population of systems (eg scientists) eventually coming to a consensus about some phenomenon (eg the value of some physical quantity?) It seems necessary to have a unified global system coordinating the whole thing.