Pyodide has numpy, scipy, matplotlib, pandas, and as of last month, even polars. https://github.com/pyodide/pyodide/pull/5282

Pyodide is far from a perfect CPython and even the packages it includes often have limitations you won't find when running natively. But there's definitely enough here to be interesting and even somewhat useful. Here's an interactive app written on Pyodide that uses astropy, numpy, and matplotlib: https://shinylive.io/py/examples/#orbit-simulation