I use KDE plasma and experience no microstutter with a Nvidia graphics card. Is there an open gnome issue for your issue on gnome?
I've tried using the triple buffering mutter patch[0] and still was experiencing issues. COSMIC is looking great but I have some weird screen artifacts randomly.
Hyprland is the only environment that hasn't had any performance issues with my 4070 Super.
[0] https://gitlab.gnome.org/GNOME/mutter/-/merge_requests/1441